Pancreatic cancer and fibrinogen storage disease
نویسندگان
چکیده
منابع مشابه
Fibrinogen storage disease without hypofibrinogenemia associated with estrogen therapy
BACKGROUND Cytoplasmic inclusion bodies within hepatocytes may have different etiologies, including the Endoplasmic Reticulum Storage Diseases (ERSDs). ERSD is a pathological condition characterized by abnormal accumulation of proteins destined for secretion in the endoplasmic reticulum of hepatocytes; it may be congenital (primary) or acquired (secondary). Fibrinogen storage disease is a form ...
متن کاملFibrinogen and cardiovascular disease.
Introduction The clear association between high fibrinogen concentrations and the risk of cardiovascular disease is of increasing practical relevance as well as scientific interest. The relation was first reported in preliminary results from the Northwick Park Heart Study in 1980' and later confirmed in its main findings.2 Numerous other prospective studies have almost without exception confirm...
متن کاملFibrinogen storage disease in a Chinese boy with de novo fibrinogen Aguadilla mutation: Incomplete response to carbamazepine and ursodeoxycholic acid
BACKGROUND Fibrinogen storage disease (FSD) is a rare autosomal-dominant disorder caused by mutation in FGG, encoding the fibrinogen gamma chain. Here we report the first Han Chinese patient with FSD, caused by de novo fibrinogen Aguadilla mutation, and his response to pharmacologic management. CASE PRESENTATION Epistaxis and persistent clinical-biochemistry test-result abnormalities prompted...
متن کاملPANCREATIC DISEASE Alcohol abuse and the risk of pancreatic cancer
Background: Although most epidemiological studies do not support a role for alcohol in the aetiology of pancreatic cancer, an increased risk among heavy drinkers cannot be excluded. Methods: In a retrospective cohort based on the Swedish Inpatient Register, we analysed the risk of pancreatic cancer among patients admitted to hospital for alcoholism (n=178 688), alcoholic chronic pancreatitis (n...
متن کاملFibrinogen Gamma Chain Mutations Provoke Fibrinogen and Apolipoprotein B Plasma Deficiency and Liver Storage
p.R375W (Fibrinogen Aguadilla) is one out of seven identified mutations (Brescia, Aguadilla, Angers, Al du Pont, Pisa, Beograd, and Ankara) causing hepatic storage of the mutant fibrinogen γ. The Aguadilla mutation has been reported in children from the Caribbean, Europe, Japan, Saudi Arabia, Turkey, and China. All reported children presented with a variable degree of histologically proven chro...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1998
ISSN: 0021-9746
DOI: 10.1136/jcp.51.11.865